Paediatric Transplantation

Nicos Kessaris and Stephen Marks: July 2018

Paediatric Transplantation General

0 CME Credits 

  • The latest trends in organ donation and kidney transplantation in the UK
  • Arterial Flow Regulator Enables Transplantation and Growth of Human Fetal Kidneys in Rats
  • Excellent outcome in infants and small children with thrombophilias undergoing kidney transplantation
  • Standardizing resistive indices in healthy paediatric transplant recipients of adult-sized kidneys
  • Transplantation of adult-sized kidneys in low-weight paediatric recipients achieves short-term outcomes comparable to size-matched grafts
  • Definitive abdominal wall closure using a porcine intestinal submucosa biodegradable membrane in paediatric transplantation
  • Outcome after kidney transplantation in children with thrombotic risk factors
  • Paediatric en bloc kidney transplantation into paediatric recipients
  • Optimizing Recovery, Utilization and Transplantation Outcomes for Kidneys From Small, < 20 kg, Paediatric Donors
  • The Evolution of Nonimmune Histological Injury and Its Clinical Relevance in Adult-Sized Kidney Grafts in Paediatric Recipients
  • A single center clinical experience in intensive care management of 104 paediatric renal transplantations between 1998 and 2002
  • The use of porcine dermal collagen implants in assisting abdominal wall closure of paediatric renal transplant recipients with donor size discrepancy
  • Early outcome in renal transplantation from large donors to small and size-matched recipients – A porcine experimental model
  • Vascular anastomosis for paediatric renal transplantation – A potential new strategy in low-weight children?
  • A critical look at the immunologically favorable adult-sized kidney transplant in small children
  • Surgical complications in live-donor paediatric and adolescent renal transplantation: Study of risk factors
  • A 100% 2-Year Graft Survival Can Be Attained in High-Risk 15-kg or Smaller Infant Recipients of Kidney Allografts
  • Combined liver-kidney transplantation in children: Indications and outcome
  • Analysis of clinical variables associated with tolerance in paediatric liver transplant recipients
  • Kidney transplantation in children weighing less than 15 kg: Extraperitoneal surgical access – experience with 62 cases
  • Reno-portal anastomosis as an approach to paediatric kidney transplantation in the setting of inferior vena cava thrombosis
  • Paediatric renal transplantation: moving forward in the field
  • Nontraditional sites for vascular anastomoses to enable kidney transplantation in patients with major systemic venous thromboses
  • Disease Beyond the Arch: A Systematic Review of Middle Aortic Syndrome in Childhood
  • Kidney Transplantation in Children
  • Successful Use of the Inferior Mesenteric Vein for Renal Transplantation
  • Insights in Transplanting Complex Paediatric Renal Recipients With Vascular Anomalies
  • Successful Renal Transplantation in Small Children With a Completely Thrombosed Inferior Vena Cava
  • Promising early outcomes with a novel, complete steroid avoidance immunosuppression protocol in paediatric renal transplantation.
  • Steroid Avoidance or Withdrawal Regimens in Paediatric Kidney Transplantation: A Meta- Analysis of Randomised Controlled Trials
  • Biologics in renal transplantation
  • Efficacy and Safety of Thymoglobulin Induction as an Alternative Approach for Steroid-Free Maintenance Immunosuppression in Paediatric Renal Transplantation
  • Steroid withdrawal in renal transplantation

Paediatric Transplantation Module 1 Kidney

3 CME Credits 

Transplanting small children (Nicos Kessaris)
  • Definition of a small child and operating techniques
  • Surgical considerations
  • Surgical complications
  • Graft and patient outcomes
Transplanting children with abnormal anatomy (Nizam Mamode)
  • Why do vascular anomalies arise and how to approach a absent IVC?
  • How do we approach an absent aorta?
  • Principles to consider and additional aids
Candidate preparation for paediatric renal transplantation (Stephen Marks)
  • Patient Evaluation
  • Choosing the donor
  • AB0 incompatible renal transplant
Immunosuppression and post-transplant care in paediatric renal transplantation (Ryszard Grenda)
  • Paediatric specificity influencing immunosuppressive protocols
  • Immunosuppressive protocols for patients at low risk
  • Immunosuppressive protocols for patients at high risk
  • Optimal immunosuppression for adolescents at risk of non-adherence
  • Basic rules of post-transplant management and monitoring in children

Paediatric Transplantation Module 2 Liver

3 CME Credits 

Late Complications in Paediatric Liver Transplantation (Stefan Schneeberger)
  • Overview and definition
  • Late Vascular Complications in Paediatric Liver Transplantation
  • Late Biliary Complications in Paediatric Liver Transplantation
  • Late Immunologic Complications in Paediatric Liver Transplantation
  • Late infectious Complications in Paediatric Liver Transplantation
  • Malignancy's after Paediatric Liver Transplantation
  • Late graft loss and Mortality after Paediatric Liver Transplantation
Anaesthetic and ITU management (Anish Gupta)
  • Chronic Liver Disease and Impact for Anaesthetists
  • Anaesthesia Assessment for Paediatric Liver Transplantation
  • Standard Anaesthetic Technique for Paediatric Liver Transplantation
  • Paediatric Liver Transplantation in Acute Liver Failure
  • Post-operative Management of the Newly Transplanted Child
Early complications after liver transplantation (Nigel Heaton)
  • Early graft function/dysfunction
  • Bleeding and hepatic artery thrombosis
  • Venous complications
  • Biliary complications
  • Miscellaneous complications
Intestinal transplantation: long term outcomes (Nigel Heaton)
  • Intestinal transplantation: Long term clinical outcomes: current status
  • Intestinal transplantation: Long term clinical outcomes: graft and patient survival
  • Intestinal transplantation: Long term clinical outcomes: Quality of life
Liver transplantation: donor selection and organ retrieval (Nigel Heaton)
  • Donor selection and retrieval: Donor selection
  • Donor selection and retrieval: Donor retrieval
  • Donor selection and retrieval: DCD donation and retrieval
  • Donor selection and retrieval: living donation
Surgical Techniques and perioperative care (Nigel Heaton)
  • Intestinal donor and grafts
  • Retrieval steps and graft variants
  • Intestinal transplantation: types of intestinal transplantations
  • Abdominal wall management
  • Living donor liver and small bowel transplantation