Transplant Bites

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  Non-adherence: A deliberate choice

  Speaker: Anna Forsberg

  
  Description: This short lecture by Anna Forsberg presents a case of non-adherence to the immunosuppressive medication after liver transplantation and the patient’s rationale behind his behaviour. Professor Forsberg discusses the reasons for being non-adherent, how transplant professionals can intervene and the fact that the patient’s meaning-making might lead to deliberate non-adherent behaviour. 
  
  

  
  

  Suggested resources:

  
  

  • Lennerling A, Kisch A, Forsberg A. Non-adherence to Immunosuppressants after Lung Transplantation – a Common Risk Behavior. The Open Nursing Journal. 2019; 13: 108-115. Doi: 10.2174/1874434601913010108.
    
    
  • Reach G, Boubaya M, Brami Y, Lévy V. Disruption in time projection and non-adherence to long-term therapies. Patient Preference and Adherence 2018; 12: 2363-2375.
    
    
  • Reach G. The mental mechanisms of patient adherence to long-term therapies, mind and care, forward by Pascal Engel, philosophy and medicine. Heidelberg: Springer; 2015:207.
    
    
  • Horne R, Chapman SCE, Parham R, Freemantle N, Forbes A, Cooper V. Understanding patients’ adherence-related beliefs about medicines prescribed for long-term conditions: A meta-analytic review of the Necessity-Concerns Framework. PLoS One 2013 ;8(12): e80633.
    
    
  • Lehane E, McCarthy G. Intentional and unintentional medication non-adherence: A comprehensive framework for clinical research practice? A discussion paper. Int J Nurs Stud 2007;44(8):1468-1477.
    

  Slides: 

• Non-adherence_A deliberative choice_Forsberg File
• This video is supported by Novartis
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  Transition in pediatric transplantation: Moving together with the Generation Alfa

  Speaker: Jelena Stojanovic

  Description: Medication nonadherence is a leading cause for allograft loss amongst adolescents and is particularly of concern during transition to adult service. This lecture by Jelena Stojanovic discusses profile of adolescents who have undergone transplant in childhood, their psychological characteristics on the background of human behaviour with recommendations on how healthcare professionals can support young people during transition therefore minimising chances for nonadherence.

   

  Suggested resources:

  • Killian MO, Triplett K, Mayersohn G, Howry SK, Masood S, Desai D. Medication Barriers and Adherence: Experiences of Pediatric Transplant Recipients. Health Soc Work. 2022 Jul 13;47(3):165-174. doi: 10.1093/hsw/hlac018.PMID: 35771953

  
  

  • Mellon L, Doyle F, Hickey A, Ward KD, de Freitas DG, McCormick PA, O'Connell O, Conlon P. Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients. Cochrane Database Syst Rev. 2022 Sep 12;9(9):CD012854. doi: 10.1002/14651858.CD012854.pub2.PMID: 36094829 Review.

  
  

  • Connett GJ, Nagra A. Ready, Steady, Go - Achieving successful transition in cystic fibrosis. Paediatr Respir Rev. 2018 Jun;27:13-15. doi: 10.1016/j.prrv.2018.05.007. Epub 2018 May 18.PMID: 29914748 Review

  
  

  • Gaete V. [Adolescent psychosocial development]. Rev Chil Pediatr. 2015 Nov-Dec;86(6):436-43. doi: 10.1016/j.rchipe.2015.07.005. Epub 2015 Sep 2.PMID: 26342392 

  
  

  • Schulz T, Niesing J, Stewart RE, Westerhuis R, Hagedoorn M, Ploeg RJ, Homan van der Heide JJ, Ranchor AV. The role of personal characteristics in the relationship between health and psychological distress among kidney transplant recipients. Soc Sci Med. 2012 Oct;75(8):1547-54. doi: 0.1016/j.socscimed.2012.05.028. Epub 2012 Jun 28.PMID: 22789461 

  Slides:

• Transition in pediatric transplantation_Stojanovic File
• This video is supported by Novartis
  

  
  

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  Making the impossible possible: Road to first-in-human kidney xenotransplant clinical trials

  
  

  Speaker: Jayme E. Locke

  This video is supported by Novartis